Analgesic , anti-inflammatory and antipyretic activity of Cissus quadrangularis

This study was intended to evaluate the analgesic anti-inflammatory and antipyretic activity of ethanolic extract of Cissus quadrangularis in experimental standard modals i.e. albino rats following oral administration. The results showed that the ethanolic extract significantly reduce the edema induced by carrageenan within 1 to 5 hrs. post dosing at all the dose levels used. On the analgesic property acetic acid induce writhing was significantly reduce in the formalin test, the extract also significantly decreases the painful stimulus in both phases of test which confirms central and peripheral effects of the drugs. Its effects on antipyretic activity were also appreciable it significantly reduces fever at higher doses within 2 hrs. on yeast induce hyperthermia in rats